Interaction of Mycobacterium tuberculosis ESAT-6 protein with ADAM9 protein
نویسندگان
چکیده
منابع مشابه
Protein-protein interactions of proteins from the ESAT-6 family of Mycobacterium tuberculosis.
In the present study, we demonstrate that, in analogy with the genes encoding ESAT-6 and CFP-10, the genes rv0287 and rv0288 from the ESAT-6 gene family are cotranscribed. Using Western-Western blotting and protein-print overlay methodologies, we demonstrate that ESAT-6 and CFP-10, as well as the protein pair Rv0288/Rv0287, interact pairwise in a highly specific way. Most notably, the ESAT-6 pr...
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The ESAT-6 antigen from Mycobacterium tuberculosis is a dominant target for cell-mediated immunity in the early phase of tuberculosis (TB) in TB patients as well as in various animal models. The purpose of our study was to evaluate the potential of ESAT-6 in an experimental TB vaccine. We started out using dimethyl dioctadecylammonium bromide (DDA), an adjuvant which has been demonstrated to be...
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ژورنال
عنوان ژورنال: African Journal of Microbiology Research
سال: 2011
ISSN: 1996-0808
DOI: 10.5897/ajmr10.856